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《一路疯狂》姐弟二人经营一辆客运大巴。在新年最后一次的旅途中，来自异域千奇百怪的乘客们带着各自的悲欢离合，夺宝之心，回归之情演绎出一场冒险喜剧的欢乐故事。。Dissolute record producer Ray Saxx finds himself thrown in jail on charges of murdering one of his top artists, an act he doesn't remember due to his characteristic drug haze. In prison, Ray is kept out of the general population and put in the K-11 unit, a pit of chronic sexual and drug abuse run by the depraved Sergeant Johnson, whose reign of terror comes to an end thanks to ...。